James Conner Week 3 Preview vs. the 49ers

Arizona Cardinals running back James Conner will face a mediocre run defense in Week 3 (Sunday at 4:25 p.m. ET), versus the San Francisco 49ers. The 49ers are ranked 13th in terms of rushing yards conceded, at 102.5 per game.

Conner has generated 73 rushing yards on 23 carries (36.5 ypg), while adding one score on the ground. Conner has recorded 23 yards on five receptions (11.5 ypg) and one receiving TD.

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Conner vs. the 49ers

• Conner vs the 49ers (since 2021): 4 GP / 63.5 RUSH YPG / 3 RUSH TD
• No player has recorded more than 100 yards on the ground in a game against the 49ers in the 2025 season.
• San Francisco has allowed one or more rushing TDs to one opposing player this year.
• No player has run for two or more TDs against the 49ers this season.
• The run defense of the 49ers is giving up 102.5 yards per game on the ground this year, which ranks 13th in the NFL.
• Opponents of the 49ers have scored one touchdown on the ground (0.5 per game). The 49ers' defense is seventh in the NFL in that category.

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Conner Rushing Insights

• Conner has come up short of his rushing yards prop bet total in each of his two games played this season.
• The Cardinals, who are 12th in NFL play in points scored, have passed 52.4% of the time while running 47.6%.
• His team has attempted 49 rushes this season. He's taken 23 of those carries (46.9%).
• Conner has a rushing touchdown in one game this season, but no games with multiple rushing TDs.
• He has scored two of his team's four offensive touchdowns this season (50.0%).
• He has four red zone rushing carries (50.0% of his team's rushing attempts inside the red zone).

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Conner's Recent Performance