Kyler Murray Week 6 Preview vs. the Colts

Arizona Cardinals quarterback Kyler Murray will be up against the Indianapolis Colts and their 19th-ranked passing defense in Week 6, starting at 1 p.m. ET on Sunday.

Murray leads Arizona with 962 passing yards (192.4 per game). Murray has also posted a 68.3% completion rate while throwing for six touchdowns and three interceptions. On the ground, Murray has rushed 29 times for 173 yards and one TD.

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Murray vs. the Colts

• Murray vs the Colts (since 2021): 1 GP / 245 PASS YPG / 1 PASS TD
• Indianapolis has given up 300 or more passing yards to just one opposing player this year.
• The Colts have allowed one or more passing touchdowns to four opposing quarterbacks this season.
• Indianapolis has given up at least two touchdown passes to two quarterbacks in 2025.
• The Colts have given up at least three TD passes in an outing to two opposing QBs this season.
• The Colts surrender 217.0 passing yards per game, the NFL's 19th-ranked pass defense this season.
• The Colts' defense is 17th in the league by allowing 1.6 passing touchdowns per game to their opponents (eight total passing TDs).

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Murray Passing Insights

• Murray has surpassed his passing yards prop total once in five chances.
• The Cardinals, who are 22nd in NFL play in points scored, have passed 56.8% of the time while running 43.2%.
• Murray's 6.0 yards per attempt rank 29th in the league.
• In four of five games this season, Murray completed a touchdown pass, including multiple TD passes twice.
• He has 70.0% of his team's 10 offensive touchdowns this season (seven).
• Murray has attempted 20 passes in the red zone (55.6% of his team's red zone plays).

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Murray's Recent Performance