Jacoby Brissett Week 11 Preview vs. the 49ers

Jacoby Brissett will be facing the 22nd-ranked passing defense in the league when his Arizona Cardinals take on the San Francisco 49ers in Week 11, on Sunday at 4:05 p.m. ET.

Brissett has piled up 1,118 passing yards this year (186.3 per game), including eight passing TDs and one pick. On the ground, Brissett has run 19 times for 82 yards and one TD, averaging 13.7 yards per game.

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Brissett vs. the 49ers

• Brissett vs the 49ers (since 2021): 2 GP / 241 PASS YPG / 1 PASS TD
• San Francisco has allowed just two opposing players to record 300 or more passing yards in an outing this year.
• The 49ers have given up one or more passing TDs to nine opposing quarterbacks this season.
• San Francisco has allowed six players to throw two or more touchdowns in a matchup in 2025.
• Three players have thrown for three or more TDs in an outing against the 49ers this season.
• The pass defense of the 49ers is conceding 228.8 yards per game this year, which ranks 22nd in the league.
• The 49ers' defense is 26th in the league by allowing 1.9 passing touchdowns per game to opponents (19 total passing TDs).

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Brissett Passing Insights

• The Cardinals, who are 25th in NFL play in points scored, have passed 58.3% of the time while running 41.7%.
• With 156 attempts for 1,118 passing yards, Brissett is 14th in league play with 7.2 yards per attempt.
• Brissett has thrown for a touchdown in four of six games this season, with more than one TD pass four times.
• He has nine total touchdowns this season (42.9% of his team's 21 offensive TDs).
• Brissett has attempted 36 passes in the red zone (38.7% of his team's red zone plays).

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Brissett's Recent Performance